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Image Search Results
Journal: World Journal of Gastroenterology
Article Title: Dihydroergotamine ameliorates liver fibrosis by targeting transforming growth factor β type II receptor
doi: 10.3748/wjg.v29.i20.3103
Figure Lengend Snippet: Dihydroergotamine alleviated fibrosis in CCl 4 -induced liver fibrosis model mice. A: The width of the portal vein (left panel); portal vein width of mice in each group (right panel, n = 7); B: The velocity of the portal vein (left panel); the velocity of mice in each group (right panel, n = 7); C: Body weight, liver weight, spleen weight, and liver weight/body weight of mice in each group ( n = 6-8); D: Gross liver specimens of the mice in each group; E: An automated biochemistry analyzer determined the enzymatic activities of serum levels of alanine aminotransferase and aspartate aminotransferase ( n = 6-7); F: Masson’s trichrome staining was performed on liver sections; G: Collagen area in Masson’s trichrome staining ( n = 7-8). All data were presented as means ± standard error of the mean. One-way ANOVA test was performed. a P < 0.05, b P < 0.01, c P < 0.001, and d P < 0.0001. TGFβ: Transforming growth factor β; TGFβR: Transforming growth factor β receptor; DHE: Dihydroergotamine.
Article Snippet: Then, the liver paraffin-embedded tissue sections were stained with a
Techniques: Staining
Journal: Journal of the Renin-Angiotensin-Aldosterone System: JRAAS
Article Title: Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice
doi: 10.1177/1470320320923977
Figure Lengend Snippet: (a) and (b) Influence of ramipril pretreatment on kidney injury . (a) Detection of kidney injury by Periodic acid-Schiff (PAS) staining 24 h post sepsis induction. Cecal ligation and puncture (CLP) operation induced an overt tubular injury in mice. Representative images are shown. The vasodilation and brush border damages are shown with asterisks on the images. Original magnification 200 ×. Bars correspond to 50 μm. N = 8–10 per group. (b) Semi-quantitative cortical tubular injury scores. The score ranges from zero to five depending on the level of tubular damage. N = 8–10, CLP versus the sham operation (SOP) group, ### p < 0.001, ramipril + SOP versus SOP group, *** p < 0.001.
Article Snippet: To estimate renal injury a Periodic acid-Schiff (PAS) stain was performed on a 4 μm paraffin kidney sections using a
Techniques: Staining, Ligation